Viewing lipid chol (cholesterol)

Coarse grained cholesterol, linked from SJ Marrink's parameter website. (ITP file contains CHOLESTEROL, CHOLESTERYL OLEATE, CHOLATE). See the website for mixed bilayers and example input files.

Cholesterol atomistic parameters developed by Monika Hoeltje and Birte Brandt (September 1998), using a force-field parameters developed by Peter Tieleman.

The lipid.itp comes from P. Tieleman's lab webpage.
The ffgmx*.* are the gromos parameters (come with Gromacs package). Both of these files are the versions available in [...] [read more]

A new GROMOS43a1-based force field (43A1-S3) for simulation of membranes with the  Gromacs simulation package. The validity of the force fields is demonstrated by correct replication of X-ray form factors and NMR order parameters over a wide range of membrane compositions in semi-isotropic NTP [...] [read more]

See http://people.su.se/~jjm/Stockholm_Lipids/Home.html for for more details and structure files to download

Cholesterol trafficking, which is an essential function in mammalian cells, is intimately connected to molecular-scale interactions through cholesterol modulation of membrane structure and dynamics and interaction with membrane receptors. Since these effects of cholesterol occur on micro- to millisecond time scales, it is essential to develop [...] [read more]